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X-WR-CALNAME:Department of Bioengineering
X-ORIGINAL-URL:https://be.iisc.ac.in
X-WR-CALDESC:Events for Department of Bioengineering
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DTSTART:20240101T000000
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BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20241213T110000
DTEND;TZID=Asia/Kolkata:20241213T120000
DTSTAMP:20260425T171545
CREATED:20241209T041739Z
LAST-MODIFIED:20241209T041821Z
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SUMMARY:BE Seminar: Cell and Gene Therapy Manufacturing: Bridging the Skillset Gap by Training the Next Generation Workforce
DESCRIPTION:Speaker: Dr. Shalu Suri\nCo-Director of Engineering Workforce Development (EWD) NSF Engineering Research Center for Cell Manufacturing Technologies (CMaT) Georgia Tech\, USA. \nDate: 13th December\nTime: 11.00 AM\nVenue: IDR Classroom – 3: G12 \nTitle: Cell and Gene Therapy Manufacturing: Bridging the Skillset Gap by Training the Next Generation Workforce \nAbstract: With the approval of the multiple cell and gene therapies by the FDA in the past few years and the tremendous promise of emerging biopharmaceutical drugs – biomanufacturing\, especially the transformative areas of cell and gene-therapy manufacturing\, has rapidly become one of the most dynamic and rapidly growing sectors of the biotech and pharma industry in the United States\, and around the world. However\, the growth of the field can only be realized by the successful development of a well-trained workforce. The lack of an adequately trained workforce has already been identified as a major barrier hindering the growth of biomanufacturing and biotherapies today and this situation will only worsen as the field continues to expand. Cell Manufacturing Technologies (CMaT)\, the NSF funded multi-institute Engineering Research Center in the Coulter Department of Biomedical Engineering at Georgia Tech\, is the first and only comprehensive multi-institute center in the world focused on developing transformative tools\, technologies\, and processes for scalable\, quality-driven biomanufacturing of cell therapies\, and preparing adequately trained workforce. Dr. Suri was recruited as Associate Director of Engineering Workforce Development (EWD) pillar of NSF CMaT ERC by Georgia Tech and Emory Medicine in Jan 2020 from Cornell University to spearhead the creation of this well-trained and diverse biomanufacturing workforce that could nurture this nascent industry and thus reduce the skillset gap. In the last 4+ years\, Dr. Suri has spearheaded multiple high-impact workforce development efforts. Of particular importance is the virtual professional training program entitled “Workforce Development in Biomanufacturing – Training in Cell and Gene Therapy” developed in collaboration with International Society for Cell and Gene Therapy (ISCT) which has trained 300+ professionals globally. In addition\, she has also led the development of a week-long hands-on Cell manufacturing training program in partnership with ISCT. Dr. Suri has championed multiple efforts at K-12 and 2-year college levels towards workforce training. She collaborates with instructors from a number of 2-year technical colleges on cell manufacturing curriculum development and its integration into their curriculum to address the shortage of entry level trained workers. In her talk she will provide a broad overview of the field and highlight the work the center has done in the last 7 years to move this field forward. \nAbout the Speaker: Dr. Shalu Suri is the Co-director of Engineering workforce Development (EWD) pillar of NSF Engineering Research Center for Cell Manufacturing Technologies (CMaT) at Georgia Tech. She joined CMaT in 2020 as the Associate Director and became the Co-director in 2022. Prior to joining GT\, she was a lecturer in BME at Cornell University where she was instrumental in designing and teaching multiple UG and graduate classes for which she received Cornell’s Teaching Excellence Award. At CMaT\, she spearheads multiple high-impact efforts across academic levels (K12-industry) towards curriculum development\, professional education\, and preparing future cell manufacturing workforce. She has received multiple honors including GT’s 2024 Outstanding Professional Education Award for her contributions to the field of professional education and GT’s 2023 Student Recognition of Excellence in Teaching CIOS Honor Roll. She serves on the National Advisory Council of NSF-InnovATEBIO biotechnology education center. She received her undergraduate degree from Kanpur University and her MS from Indian Institute of Technology Bombay (India)\, and her PhD in Biomedical Engineering from the University of Texas at Austin. She received her postdoctoral training from Georgia Tech.
URL:https://be.iisc.ac.in/event/be-seminar-cell-and-gene-therapy-manufacturing-bridging-the-skillset-gap-by-training-the-next-generation-workforce/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
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DTSTART;TZID=Asia/Kolkata:20241216T160000
DTEND;TZID=Asia/Kolkata:20241216T170000
DTSTAMP:20260425T171545
CREATED:20241204T102338Z
LAST-MODIFIED:20241204T102338Z
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SUMMARY:BE Seminar: Mesoscale Epithelial Mechanobiology and Cellular Interfaces
DESCRIPTION:Speaker: Dr. Jacopo Di Russo\nGroup Leader\nInstitute of Molecular and Cellular Anatomy\, RWTH Aachen University\n& Leibniz-Institute for Interactive Materials\, Aachen Germany. \nTitle: Mesoscale Epithelial Mechanobiology and Cellular Interfaces \nAbstract: Mechanical properties regulate tissue functions at a multicellular length scale or mesoscale. These properties depend on the interaction of cells with their interfaces\, hence on the balance between intercellular tension and the extracellular matrix (ECM) adhesion forces.\nDr. Jacopo Di Russo’s group aims to dissect the role of cell-ECM and cell-cell communication in epithelial mechanobiology\, starting from the medically relevant retinal epithelium. In contrast to the experimental investigation of traditional biological sciences\, his laboratory uses cross-disciplinary approaches combining synthetic hydrogels with stem cell-based models. They particularly develop and adapt biohybrid systems where cells interact with hydrogels that are designed to control cell-cell or cell-ECM adhesion. Synthetic material allows the unique reduction of the degree of freedom in the cellular/tissue system\, thus helping us to reveal phenotypical tissue plasticity and molecular function.\nThe talk will first give an overview of published work1\,2 on understanding how ECM physical (elasticity) and biochemical cues (receptor density) impact epithelial system properties\, namely stress heterogeneity and intercellular force coordination. The talk will also show that these properties are not only in vitro observations but play pivotal roles in controlling the vision. A density gradient of ECM characterises the contractility of the retinal epithelium in vivo and modulates its efficiency in supporting photoreceptor cells’ homeostasis. Furthermore\, Dr. Jacopo will show data from the ongoing work which addresses different aspects of the mechanobiology of tissue ageing. They optimised a phototunable hydrogel as substrates for epithelia to model ECM local remodelling on demand. Moreover\, we developed microgels used as phototunable phantom cells to simulate age-related tissue mechanical anisotropy. Altogether\, They can dissect the relationship between tissue mechanics and function by controlling the temporal and spatial properties of cellular interfaces. \nAbout the Speaker: Dr. Jacopo Di Russo studied cell biology in Florence (Italy) for then joining the laboratory of Prof. Lydia Sorokin in Muenster (Germany) as Marie Curie Fellow. There he studied how extracellular matrix influences physiological responses. In 2015 he joined the laboratory of Prof. Joachim Spatz at the Max Planck Institute for Medical Research in Heidelberg (Germany) deepening his knowledge on cell adhesion at biophysical levels. Since 2019 he is an independent group leader at the Interdisciplinary Center for Clinical Research of the RWTH Aachen. Jacopo Di Russo’s research aims to understand the interplay of extracellular matrix biochemical and physical information in controlling epithelial mechanobiology. \nDate: 16th December \nTime: 4.00 PM\nVenue: IDR Classroom – 05: G21
URL:https://be.iisc.ac.in/event/be-seminar-mesoscale-epithelial-mechanobiology-and-cellular-interfaces/
CATEGORIES:Seminar
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