BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Department of Bioengineering - ECPv5.14.0.2//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Department of Bioengineering
X-ORIGINAL-URL:https://be.iisc.ac.in
X-WR-CALDESC:Events for Department of Bioengineering
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Asia/Kolkata
BEGIN:STANDARD
TZOFFSETFROM:+0530
TZOFFSETTO:+0530
TZNAME:IST
DTSTART:20240101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20241216T160000
DTEND;TZID=Asia/Kolkata:20241216T170000
DTSTAMP:20260406T044302
CREATED:20241204T102338Z
LAST-MODIFIED:20241204T102338Z
UID:4395315-1734364800-1734368400@be.iisc.ac.in
SUMMARY:BE Seminar: Mesoscale Epithelial Mechanobiology and Cellular Interfaces
DESCRIPTION:Speaker: Dr. Jacopo Di Russo\nGroup Leader\nInstitute of Molecular and Cellular Anatomy\, RWTH Aachen University\n& Leibniz-Institute for Interactive Materials\, Aachen Germany. \nTitle: Mesoscale Epithelial Mechanobiology and Cellular Interfaces \nAbstract: Mechanical properties regulate tissue functions at a multicellular length scale or mesoscale. These properties depend on the interaction of cells with their interfaces\, hence on the balance between intercellular tension and the extracellular matrix (ECM) adhesion forces.\nDr. Jacopo Di Russo’s group aims to dissect the role of cell-ECM and cell-cell communication in epithelial mechanobiology\, starting from the medically relevant retinal epithelium. In contrast to the experimental investigation of traditional biological sciences\, his laboratory uses cross-disciplinary approaches combining synthetic hydrogels with stem cell-based models. They particularly develop and adapt biohybrid systems where cells interact with hydrogels that are designed to control cell-cell or cell-ECM adhesion. Synthetic material allows the unique reduction of the degree of freedom in the cellular/tissue system\, thus helping us to reveal phenotypical tissue plasticity and molecular function.\nThe talk will first give an overview of published work1\,2 on understanding how ECM physical (elasticity) and biochemical cues (receptor density) impact epithelial system properties\, namely stress heterogeneity and intercellular force coordination. The talk will also show that these properties are not only in vitro observations but play pivotal roles in controlling the vision. A density gradient of ECM characterises the contractility of the retinal epithelium in vivo and modulates its efficiency in supporting photoreceptor cells’ homeostasis. Furthermore\, Dr. Jacopo will show data from the ongoing work which addresses different aspects of the mechanobiology of tissue ageing. They optimised a phototunable hydrogel as substrates for epithelia to model ECM local remodelling on demand. Moreover\, we developed microgels used as phototunable phantom cells to simulate age-related tissue mechanical anisotropy. Altogether\, They can dissect the relationship between tissue mechanics and function by controlling the temporal and spatial properties of cellular interfaces. \nAbout the Speaker: Dr. Jacopo Di Russo studied cell biology in Florence (Italy) for then joining the laboratory of Prof. Lydia Sorokin in Muenster (Germany) as Marie Curie Fellow. There he studied how extracellular matrix influences physiological responses. In 2015 he joined the laboratory of Prof. Joachim Spatz at the Max Planck Institute for Medical Research in Heidelberg (Germany) deepening his knowledge on cell adhesion at biophysical levels. Since 2019 he is an independent group leader at the Interdisciplinary Center for Clinical Research of the RWTH Aachen. Jacopo Di Russo’s research aims to understand the interplay of extracellular matrix biochemical and physical information in controlling epithelial mechanobiology. \nDate: 16th December \nTime: 4.00 PM\nVenue: IDR Classroom – 05: G21
URL:https://be.iisc.ac.in/event/be-seminar-mesoscale-epithelial-mechanobiology-and-cellular-interfaces/
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250109T143000
DTEND;TZID=Asia/Kolkata:20250110T170000
DTSTAMP:20260406T044302
CREATED:20250109T042330Z
LAST-MODIFIED:20250109T050800Z
UID:4395319-1736433000-1736528400@be.iisc.ac.in
SUMMARY:11th Annual Symposium\, BE 2025
DESCRIPTION:11th Annual Symposium\, BE 2025 \n \n \n  \nBE Symposium Schedule: Click here
URL:https://be.iisc.ac.in/event/11th-annual-symposium-be-2025/
LOCATION:TCS Smart-X Hub Building\, IISc
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250310T160000
DTEND;TZID=Asia/Kolkata:20250310T170000
DTSTAMP:20260406T044302
CREATED:20250305T043555Z
LAST-MODIFIED:20250305T043555Z
UID:4395499-1741622400-1741626000@be.iisc.ac.in
SUMMARY:BE Seminar\, Pooled Microscopy-Based CRISPR Screens by Dr. Krishna Choudhary
DESCRIPTION:Speaker: Dr. Krishna Choudhary\nPostdoctoral Scholar\, University of California\, San Francisco. \nDate:10th March\nTime: 4.00 PM\nVenue: TCS Smart X Building\, Classroom 03 – (G F – 12) \nTitle: Pooled Microscopy-Based CRISPR Screens \nAbstract: Pooled CRISPR screens have revolutionized the process of identifying genetic targets for drug development. Traditional CRISPR screens typically focus on a single phenotype\, such as cell death. While this has provided valuable insights into gene essentiality and resistance to cell death\, it has generally failed to uncover functional information for most of the genome. Pooled screening lacks the richness of data achievable through microscopy-based phenotypic screens. \nArrayed microscopy-based screens offer more detailed insights into cancer cell states\, such as cell morphology and subcellular protein localization. However\, the challenges associated with executing large-scale arrayed screens and analyzing the resulting images have limited the scalability and accessibility of high-content microscopy-based CRISPR screens. \nIn this talk\, He will present an integrated wet lab and computational platform for pooled microscopy-based CRISPR screens. His technology uses epitope combinations attached to a fluorescent protein to barcode CRISPR guide identities. Combined with multiplexed immunofluorescence microscopy\, which enables the simultaneous quantification of multiple phenotypic markers and CRISPR guide identities at the single-cell level\, this platform allows for the pooling of CRISPR perturbations. By reducing the cost and manual labor requirements\, his work will democratize the use of microscopy-based CRISPR screens\, accelerating therapeutic target discovery and drug development. \nAbout the Speaker: Dr.Krishna is a bioengineer and data scientist with expertise in developing high-throughput technologies that bridge wet lab biology and data science. His published work spans a range of biological systems\, from microbes and RNA viruses to yeast\, neurological disorders\, and cardiovascular disease models. He actively collaborates with diverse biomedical researchers to drive innovations that may translate into impactful therapies and diagnostics for human health. \nDr. Krishna earned his BTech and MTech in Biochemical Engineering and Biotechnology from IIT Delhi (2013). He then completed his Ph.D. at the University of California\, Davis in 2019\, where his research focused on developing statistical methods for the analysis of high-throughput sequencing-based RNA structurome profiling data. Following his PhD\, Krishna worked as a bioinformatician/statistician at the Gladstone Institutes\, San Francisco\, where he gained experience with diverse sequencing-based assays and single-cell technologies. In 2021\, he began postdoctoral training at the University of California San Francisco\, where he expanded his research skill set in the wet lab\, gaining expertise in synthetic biology\, CRISPR technologies\, and high-content microscopy. \nIn the future\, Dr. Krishna aims to continue exploring the genetic basis of complex diseases\, with a focus on developing precision therapies and novel diagnostic tools. His interdisciplinary training in both computational and experimental approaches positions him to make meaningful contributions to the field of bioengineering and data-driven healthcare innovation.
URL:https://be.iisc.ac.in/event/be-seminar-pooled-microscopy-based-crispr-screens-by-dr-krishna-choudhary/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250312T160000
DTEND;TZID=Asia/Kolkata:20250312T170000
DTSTAMP:20260406T044302
CREATED:20250305T043704Z
LAST-MODIFIED:20250305T043704Z
UID:4395501-1741795200-1741798800@be.iisc.ac.in
SUMMARY:BE Seminar: Dynamical Complexity in Microbial Matter by Dr. Praneet Prakash
DESCRIPTION:Speaker: Dr. Praneet Prakash\,\nPostdoctoral Researcher\, University of Cambridge\, UK. \nDate: 12th\, March\nTime: 4.00 PM\nVenue: TCS Smart X Building\, Classroom No.3 (GF -12). \nTitle: Dynamical Complexity in Microbial Matter \nAbstract: Microorganisms inhabit highly fluctuating natural environments and survive in a low-nutrient resource bath. It is now well-recognized that nutrient exchanges among microbes play a vital role in their survival. The existence of such exchanges raises fundamental questions about the dynamics of these interactions. \nIn this talk\, he will explore experimentally and theoretically a realization of such interactions in which active bacteria dynamically respond to the oxygen produced by immotile green algae through photosynthesis. Even in this simplest mixture of active-passive suspensions\, we find complex dynamics involving nutrient exchanges. \nToward the end of the talk\, he will briefly discuss our investigations on the collective behaviour of a living fluidic network\, which presents another fascinating example of dynamical complexity in microbial matter. \nAbout the Speaker: Dr. Praneet Prakash received PhD from the Indian Institute of Science\, Bangalore\, and is currently a postdoctoral researcher at the School of Physical Sciences\, University of Cambridge. His research interests include Microbial Biophysics\, Biofluids\, and Complex Living Systems.
URL:https://be.iisc.ac.in/event/be-seminar-dynamical-complexity-in-microbial-matter-by-dr-praneet-prakash/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250313T140000
DTEND;TZID=Asia/Kolkata:20250313T150000
DTSTAMP:20260406T044302
CREATED:20250311T070224Z
LAST-MODIFIED:20250311T070224Z
UID:4395505-1741874400-1741878000@be.iisc.ac.in
SUMMARY:BE Seminar: Harnessing Nanoscale Cellular Communication for Designing Next-Generation Therapeutics by Dr. Tanmoy Saha\,
DESCRIPTION:Speaker: Dr. Tanmoy Saha\, MSc\, PhD. \nInstructor\, Harvard Medical School \nAssociate Bioengineer\, Brigham and Women’s Hospital \nDate: 13th March\nTime: 2.00 PM\nVenue: TCS Smart X Building\, Seminar Hall – (G F – 22) \nTitle: Harnessing Nanoscale Cellular Communication for Designing Next-Generation Therapeutics \nAbstract: Aberrant intercellular communication underlies disease progression. For example\, cancer cells communicate with neighboring cells to exchange organelles\, proteins\, metabolites\, and ions\, which helps them gain survival advantages. He is interested in three different types of communication: (i) transmembrane ionic communication\, (ii) extracellular protein-mediated communication\, and (iii) intercellular nanoscale physical communication. \nCells maintain an ionic homeostasis with the extracellular environment using ion channels and transporters. He has developed a variety of unimolecular and supramolecular artificial chloride channels (ACT). The ACTs are robust supramolecular architecture made up of small molecules. This helps in a better understanding of ion transport activity and modulating ionic communication in cells. He has performed structure-activity relationships to identify the best ACT. He introduced the first-ever example of ACT\, which can induce apoptosis in cancer cells by disrupting ionic homeostasis. \nCancer cells use extracellular proteins\, known as immune checkpoints\, to send kill-me-not signals to T cells and macrophages. Immunotherapy has made a paradigm shift in cancer treatment by blocking such interactions using monoclonal antibodies. However\, more than 70% of cancer patients do not respond to immunotherapy. He has introduced immunoengineered nanotherapeutics that serve as a platform technology to deliver a combination of pharmacological drugs and biologics to cancer cells. This nanotherapeutic can block more than one immune checkpoint and activate both innate and adaptive immunity. This has shown increased therapeutic efficacy in syngeneic lung cancer\, which is not responsive to traditional immunotherapy and monotherapies. \nFurthermore\, they investigated a novel mechanism of immune evasion by cancer cells through nanoscale physical communication. They have used high-resolution electron and optical microscopy to identify the nanoscale communication of the cancer cells with T cells and hijack mitochondria. The transfer of mitochondria metabolically empowers the cancer cells and increases their proliferation\, metastasis\, and drug resistance. In contrast\, the T cell population depletes because of metabolic deactivation. Blocking the nanotube-mediated mitochondria transfer by pharmacological inhibitors has shown potential therapeutic implications in increasing intrinsic T cell immune response and elevating therapeutic efficacy in combination with traditional immunotherapy. Moreover\, they have shown elevating the immune response by supercharging T cells with exogenous mitochondria. Hence\, a mechanistic understanding of cellular communication and novel therapeutic strategies are critical to offer better therapeutic outcomes in cancer and other chronic diseases. \nAbout the Speaker: Dr. Saha is an entry-level faculty at Harvard Medical School and an Associate Bioengineer at Brigham and Women’s Hospital. He has received PhD from the Indian Institute of Science Education and Research Pune and received the best thesis award from the chemistry department. Dr. Saha’s. major research direction is to develop tools to study cellular communication and introduce novel therapeutic strategies. He has published his research in prestigious journals\, including Nature Nanotechnology\, Science Advances\, J. Am. Chem. Soc.\, Cell\, PNAS\, etc. He has received independent research grants from the Department of Defense and Melanoma Research Alliance.
URL:https://be.iisc.ac.in/event/be-seminar-harnessing-nanoscale-cellular-communication-for-designing-next-generation-therapeutics-by-dr-tanmoy-saha/
LOCATION:TCS Smart-X Hub Building\, IISc
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250313T160000
DTEND;TZID=Asia/Kolkata:20250313T170000
DTSTAMP:20260406T044302
CREATED:20250311T070053Z
LAST-MODIFIED:20250311T070053Z
UID:4395503-1741881600-1741885200@be.iisc.ac.in
SUMMARY:BE Seminar: Modeling complex phenotypes supported by gene regulatory networks by Dr. Tomas Gedeon
DESCRIPTION:Speaker: Dr. Tomas Gedeon\nDate: 13th March\nTime: 4.00 PM\nVenue: TCS Smart X Building\, Classroom 03 – (G F – 12) \nTitle: Modeling complex phenotypes supported by gene regulatory networks \nAbstract: Gene regulatory networks with more than a few genes can support different phenotypes in different conditions. These conditions may be external inputs like intercellular signaling\, resource abundance\, or internal variability like abundance of ribosomes\, RNAP\, or even copy number of different enzymes. The different conditions can be modeled as changes in the parameters of a gene network model. \nThe mathematical challenge is to develop methods to describe\, search\, and analyze the behavior of models across large sets of parameters. He will illustrate the use of the techniques that we developed\, which are based on combining discrete Boolean approaches with differential equations models\, on three problems: \nThe first problem studies a problem where naive CD4+ cells differentiate into Th1\, Th2\, Th17\, and Treg subsets which mutually inhibit each other. in their model\, they compare the prevalence\, across all parameters\, of a fully differentiated cell type to a cell type that combines characteristics of two of the four types. They find that such a type of hybrid occurs\nmore frequently. This suggests that differentiation to four types likely happens in a two-step process\, rather than in a single step. The model is general and conclusions may apply to other differentiation processes. \nThe second problem concerns the ability of the same cell cycle network in yeast to support two phenotypes: (a) regular cell cycle\, and (b) endocycling\, where the cell duplicates the genome but does not go through mitosis. Endocycling can be induced experimentally by knocking down mitotic cyclin and they use the data to show that\, indeed\, a single network in different parameter regimes\, can support these different phenotypes. \nThe third problem concerns the gap gene network in Drosophila. Maternal gradients provide cell-specific input into the gap gene network along the head-to-tail axis. They investigate if this varying input\, interpreted as varying specification of parameters of the gap gene network\, is sufficient to explain different states that the network reaches in different segments\, which lays down the segmentation plan for the animal. \nIf interest and time remain\, He will explain a bit of the mathematics that allows us to do this type of analysis. \nAbout the Speaker: Dr. Tomas Gedeon is a Professor of Mathematics at Montana State University who specializes in mathematical modeling of biological systems\, especially those arising in cellular and molecular biology. His most recent interest is to develop new methods to understand the behavior of gene regulatory networks with applications to apply understanding of cell cycle and behavior of developmental networks across time and space. He obtained his undergraduate degree from Comenius University in his native Slovakia in 1989 and a PhD in Mathematics from Georgia Institute of Technology in 1994.
URL:https://be.iisc.ac.in/event/be-seminar-modeling-complex-phenotypes-supported-by-gene-regulatory-networks-by-dr-tomas-gedeon/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250321T160000
DTEND;TZID=Asia/Kolkata:20250321T170000
DTSTAMP:20260406T044302
CREATED:20250320T045937Z
LAST-MODIFIED:20250320T045937Z
UID:4395507-1742572800-1742576400@be.iisc.ac.in
SUMMARY:BE Seminar: BioMedical Printing Technology – from Vascularized OOCs to Cellular Agriculture by Dr. Andreas Blaeser
DESCRIPTION:Speaker: Dr. Andreas Blaeser\nDate: 21st March\nTime: 4.00 PM\nVenue: TCS Smart X Building\, Classroom 03 – (G F – 12) \nTitle: BioMedical Printing Technology – from Vascularized OOCs to Cellular Agriculture \nAbstract: The field of biomedical printing encompasses various techniques for the bio fabrication of living tissue. Among these\, 3D bioprinting is the best known. It is used to print living cells embedded in a hydrogel precursor in layers to form a three-dimensional tissue precursor. These can be further developed into biological implants for regenerative medicine (bone\, muscle\, cartilage) or processed into miniaturised in vitro models for drug testing (e.g. organ-on-a-ship systems). The lecture will give a brief overview of existing bioprinting methods and also discuss novel printing mechanisms for the large-scale production of cellular agriculture products (e.g. cultured meat). Finally\, a link will be made to industrial printing by presenting a newly developed 3D printing system for the production of comparatively light components for bioinspired architecture and design. \nAbout the speaker: Andreas Blaeser is a professor of “BioMedical Printing Technology” at the Technical University of Darmstadt in Germany and Director of the Institute for Printing Science and Technology (IDD). He conducts research in the field of bio fabrication\, production and joining technology of biologized functional materials. In this role\, he leads and develops an interdisciplinary team of scientists and teaches interdisciplinary subjects on Biomaterials\, Tissue Engineering\, Bio fabrication\, and 3D-Bioprinting Technology as part of the master programs “Mechanical and Process Engineering”\, and “Synthetic Biology” as well as in the Bachelor program “Bio-Materials Engineering”. The focus of his research and teaching is on bringing together living cells\, hydrogels\, and engineering materials with special mechanical\, chemical\, and electrical properties. His work provides the basis for the future production of bioartificial tissues\, “sentient” robotics\, and renewable semi-finished products. These can be used\, for example\, as implants in regenerative medicine\, as sensor-integrated in vitro models for drug and toxicity studies\, as artificial skin of soft robotics elements\, or as sustainable bioartificial consumer goods (e.g. cultured meat).
URL:https://be.iisc.ac.in/event/be-seminar-biomedical-printing-technology-from-vascularized-oocs-to-cellular-agriculture-by-dr-andreas-blaeser/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250519T160000
DTEND;TZID=Asia/Kolkata:20250519T170000
DTSTAMP:20260406T044302
CREATED:20250514T070237Z
LAST-MODIFIED:20250514T070237Z
UID:4395600-1747670400-1747674000@be.iisc.ac.in
SUMMARY:BE Seminar: Indigenous technologies for Gene therapy: Progress and Prospects
DESCRIPTION:Title: Indigenous technologies for Gene therapy: Progress and Prospects \nSpeaker: Dr. Jayandharan Rao\, \nAbstract: The most important component of gene therapy in humans is the choice of an efficient and safe gene delivery system\, otherwise known as vectors. Viruses have emerged as important tools for this purpose. This is due to their natural ability to target specific tissues in humans. Several limitations\, most notably the immunological barriers related to the recipient and the virus shell\, preclude the universal application of viral vectors such as AAV. Unravelling how host cells perceive viral intrusion and their immediate and long-lived response to this process is thus crucial. Our idea is to traverse and investigate aspects of the virus life cycle\, dissect the tug-of-war initiated between these players to establish primacy\, and dwell on how it is possible to alter this milieu in favor of the virus to generate improved gene delivery strategies. Dr.Jayandharan believes that this multi-pronged and comprehensive approach to develop an AAV-based vector system encompassing the basic biology of the virus and pre-clinical validation in different disease models [Leber congenital amarousis\, muscular dystrophy\, diabetes\, etc.] augurs well for their potential use in humans. Based on these concepts\, we have developed highly efficient AAV-based gene therapy approaches for their potential therapeutic use. Their lab routinely tests some of the exciting leads gathered by our understanding of AAV-host interactions in preclinical models of genetic disorders. \nAbout The Speaker: Prof. Rao is currently a Professor in IIT Kanpur. His group specializes in gene therapy. He is working on fostering equitable access for gene and cell therapy products around the world. \n 
URL:https://be.iisc.ac.in/event/be-seminar-indigenous-technologies-for-gene-therapy-progress-and-prospects/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250616T110000
DTEND;TZID=Asia/Kolkata:20250616T170000
DTSTAMP:20260406T044302
CREATED:20250610T084306Z
LAST-MODIFIED:20250610T084306Z
UID:4395607-1750071600-1750093200@be.iisc.ac.in
SUMMARY:BE Seminar: Are these problems or are these opportunities?
DESCRIPTION:Speaker: Dr. Anuradha Chandramohan\nCMC\, Vellore \nDate: 16th June\nTime: 11.00 AM\nVenue: GF – 12\, TCS Smart X Building \nTitle: Are these problems or are these opportunities? \nAbstract: Imaging plays a critical role in diagnosing diseases\, mapping their extent for therapeutic decision-making\, assessing treatment response\, and prognostication. Beyond these core functions\, there is growing interest in opportunistic screening to identify life-threatening cardiovascular events and reduce mortality. In this presentation\, she would like to focus on the following aspects of onco-imaging: predicting response to treatment\, prognostic imaging biomarkers\, the need for improving our understanding of the connection between lymph nodes and cancers\, and the scope of opportunistic screening for patients with treatable cancer and cancer survivors. Lastly\, she would like to touch upon the opportunities and worries of integrating language models into research and routine clinical care. She sees all these as both problem areas and immense opportunities for us to collaborate and find solutions together.\nAbout The Speaker: Dr. Anuradha Chandramohan is a Professor of Radiology and the Clinical Lead of Abdominal Imaging at Christian Medical College Vellore. She specialises in onco-imaging with a keen research focus on colorectal cancer\, peritoneal malignancy\, and gynaecological oncology. Having trained at top cancer centres in the UK and USA\, she is well-published\, has lectured at major conferences\, has held academic portfolios at the state and National Radiology Societies\, and is currently the Associate Editor of the Indian Journal and Radiology and Imaging and Journal of Gastrointestinal and Abdominal Radiology. She was a faculty member at international conferences such as the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) annual conference and the Asia Oceanian Congress of Radiology this year. In the latter\, she delivered the India-Japan joint symposium on the contributions of imaging in peritoneal surface malignancies. Her contributions extend to developing quality indicators for onco-imaging with the National Cancer Grid\, India\, and enhancing synoptic reporting for abdominal and pelvic cancers through the NCG-Koita Centre of Digital Oncology. Guided by her core values of excellence\, love\, live\, and give\, she is committed to making radiology education\, research\, and practice in India more patient-centric\, accessible\, and cost-effective.
URL:https://be.iisc.ac.in/event/be-seminar-are-these-problems-or-are-these-opportunities/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250626T160000
DTEND;TZID=Asia/Kolkata:20250626T170000
DTSTAMP:20260406T044302
CREATED:20250619T062458Z
LAST-MODIFIED:20250619T062458Z
UID:4395609-1750953600-1750957200@be.iisc.ac.in
SUMMARY:BE Seminar by Dr. Abhishek Jain: Convergence Engineering: Vascular & Cancer Medicine with Organ-Chips on Earth and Space
DESCRIPTION:Speaker: Dr. Abhishek Jain\nDepartment of Biomedical Engineering\nCollege of Engineering\nDepartment of Medical Physiology\nSchool of Medicine\nTexas A&M University. \nTitle: Convergence Engineering: Vascular & Cancer Medicine with Organ-Chips on Earth and Space\nAbstract: The perpetual rise in cost of healthcare is one of the biggest socioeconomic problems of our globe. Part of the challenge is that productivity of drug companies is declining\, and relatively fewer drugs are reaching market. This is partly so because drug discovery largely rests on the results from animal studies\, which can turn into negative outcomes in human clinical trials. The Jain lab creates microphysiological systems and convergent technologies that predict human physiology and complement in vivo studies. By establishing and leveraging extensive collaborations across academia\, medical centers\, and space industry\, they have made contributions in advancing the fundamental knowledge and drug discovery of ageing\, thrombosis\, ovarian cancer\, and lymphedema. Here\, a few examples of their approach will be presented.\nDr. Abhishek Jain is an Associate Professor of Biomedical Engineering and holds the Barbara and Ralph Cox’53 faculty fellow position at Texas A&M University. He is a founder of several next generation organ-on-chips and companion technologies of complex transport systems and AI-based analytics. His lab particularly specializes in engineering and commercializing patient-specific organ-chip platforms of cardiovascular and cancer medicine. They are recognized as leaders of integrating blood and lymphatic microcirculation in engineered cell systems.
URL:https://be.iisc.ac.in/event/be-seminar-by-dr-abhishek-jain-convergence-engineering-vascular-cancer-medicine-with-organ-chips-on-earth-and-space/
LOCATION:IDR Building – G12: Classroom 3
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20250821T100000
DTEND;TZID=Asia/Kolkata:20250821T170000
DTSTAMP:20260406T044302
CREATED:20250814T041404Z
LAST-MODIFIED:20250814T041404Z
UID:4395676-1755770400-1755795600@be.iisc.ac.in
SUMMARY:BE: Seminar on Harnessing Nanoscale Cellular Communication for Designing Next-Generation Therapeutics by Dr. Tanmoy Saha
DESCRIPTION:Speaker: Tanmoy Saha\, MSc\, PhD.\nInstructor at Harvard Medical School\nAssociate Bioengineer at Brigham and Women’s Hospital \nDate: 21st August 2025\nTime: 10.00 AM\nVenue: GF – 22\, TCS Smart X Hub (TSH) Building \nTitle: Harnessing Nanoscale Cellular Communication for Designing Next-Generation Therapeutics\nAbstract: Cellular communication plays a critical role in physiology. Aberrant intercellular communication underlies disease progression. For example\, cancer cells communicate with neighboring cells to exchange organelles\, proteins\, metabolites\, and ions\, which helps them gain survival advantages. I am interested in studying communication at the subcellular and cellular levels\, such as: (i) transmembrane ionic communication\, (ii) extracellular protein-mediated communication\, and (iii) intercellular nanoscale physical communication.\nCells maintain an ionic homeostasis with the extracellular environment using ion channels and transporters. I have developed a variety of artificial chloride channels (ACT). The ACTs are robust supramolecular architectures made up of small molecules. This helps in a better understanding of ion transport activity and modulating ionic communication in cells. I introduced the first-ever example of ACT\, which can induce apoptosis in cancer cells by disrupting ionic homeostasis.\nCancer cells communicate with immune cells via extracellular proteins\, known as immune checkpoints. They send kill-me-not signals to T cells and macrophages. Immunotherapy has made a paradigm shift in cancer treatment by blocking such interactions\, but effective in less than 30% of patients. I have introduced immunoengineered nanotherapeutics that serve as a unified platform to deliver a combination of pharmacological drugs and biologics to cancer cells. The bifunctional nanotherapeutic can activate both innate and adaptive immunity by blocking PDL1 and CD47 immune checkpoints. This has shown increased therapeutic efficacy in syngeneic lung cancer\, which is not responsive to traditional immunotherapy.\nFurthermore\, we investigated a novel mechanism of immune evasion by cancer cells through nanoscale physical communication. We have used high-resolution electron and optical microscopy to identify that the cancer cells hijack mitochondria from T cells using nanoscale tubular communication. The transfer of mitochondria energetically empowers the cancer cells and increases their proliferation\, metastasis\, and drug resistance. In contrast\, the T cell population depletes because of the lack of energy production. Blocking the nanotube-mediated mitochondria transfer by pharmacological inhibitors has shown potential therapeutic implications in increasing intrinsic T cell immune response and elevating therapeutic efficacy in combination with traditional immunotherapy. Moreover\, we have shown elevating the immune response by supercharging T cells with exogenous mitochondria. Hence\, a mechanistic understanding of cellular communication\, the development of novel therapeutic strategies\, and delivering them to the specific cells are critical for designing better therapeutic strategies in cancer and other chronic diseases.\nAbout the Speaker: Dr. Saha is an entry-level faculty member at Harvard Medical School and an Associate Bioengineer at Mass General Brigham. He has completed an MSc from Visva Bharati University and a PhD from the Indian Institute of Science Education and Research Pune. Dr. Saha’s major research direction is to develop tools to study cellular communication and introduce novel therapeutic strategies. He has published his research in prestigious journals\, including Nature Nanotechnology\, Science Advances\, and J. Am. Chem. Soc.\, Cell\, PNAS\, etc. He has received independent research grants from the Department of Defense and the Melanoma Research Alliance and many awards\, including the best thesis award\, Scholar in Training Award\, etc.
URL:https://be.iisc.ac.in/event/be-seminar-on-harnessing-nanoscale-cellular-communication-for-designing-next-generation-therapeutics-by-dr-tanmoy-saha/
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20251007T100000
DTEND;TZID=Asia/Kolkata:20251007T110000
DTSTAMP:20260406T044302
CREATED:20250930T060748Z
LAST-MODIFIED:20250930T060748Z
UID:4395704-1759831200-1759834800@be.iisc.ac.in
SUMMARY:BE Seminar: From design to healing: Engineering stimuli-responsive function biomaterials for advanced therapeutics
DESCRIPTION:Speaker: Dr. Sayan Deb Dutta\nSenior postdoctoral research fellow\nBiorobotics Research Group\, Kangwon National University\, South Korea. \nDate: 7th October 2025\nTime: 10.00 AM\nVenue: GF – 22\, TCS Smart X Hub (TSH) Building \nTitle: From design to healing: Engineering stimuli-responsive function biomaterials for advanced therapeutics \nAbstract: Stimuli-responsive smart biomaterials are revolutionizing advanced therapeutics by actively sensing and responding to physiological or external cues\, such as pH\, temperature\, enzymes\, light\, or magnetic fields. Unlike traditional scaffolds\, these systems provide precise control over drug release\, immune regulation\, and tissue repair\, making them highly promising for chronic wound healing and regeneration. Advances in 3D printing/ bioprinting enable the fabrication of patient-specific\, hierarchical constructs with spatially organized therapeutic components. The integration of functional nanomaterials—including 1D materials\, 2D nanosheets (e.g.\, graphene\, gC3N4\, MXenes)\, and hybrid architectures—enhances responsiveness\, mechanical robustness\, and therapeutic delivery. Embedding flexible bioelectronics\, such as photonic nanocrystals and conductive nanofillers\, further enables real-time health sensing and feedback-controlled therapy\, merging regenerative medicine with digital health technologies. In parallel\, the incorporation of therapeutic molecules\, such as exosomes and small peptides\, promotes angiogenesis\, reduces oxidative stress\, and modulates the immune response\, thereby accelerating the healing process. Applications extend beyond medicine to cellular agriculture\, where bioprinted adaptive scaffolds support cultured tissues and sustainable protein production\, leading to eco-friendly meat cultivation. Moreover\, advanced bioimaging probes (e.g.\, carbon dots) enable non-invasive\, high-resolution monitoring of biomaterial–cell interactions\, tumor imaging\, and in situ tissue remodeling. Together\, these innovations establish next-generation stimuli-responsive multifunctional platforms\, paving the way for personalized\, durable\, and adaptive healthcare solutions. \nAbout the Speaker: Dr. Sayan Deb Dutta holds a Ph.D. degree in biosystems engineering with a major in biomaterials science and engineering. Currently\, he serves as a senior postdoctoral research fellow at the Biorobotics Research group\, Kangwon National University\, South Korea. He joined as a visiting research fellow at the School of Medicine\, University of California\, Davis. He completed his master’s degree at the University of Kalyani\, West Bengal\, India. Over the past six years\, he has been involved in the biomedical engineering field\, where he has developed multi-material bioinks\, primarily based on natural biopolymers\, proteins\, and carbohydrates\, for 3D printing/bioprinting\, immunomodulation\, and tissue engineering applications. His current research focuses on the development of naturally inspired flexible bioelectronics\, stimuli-responsive 3D scaffolds\, and the fabrication of bioactive nanomaterials (e.g.\, homogeneous and heterogeneous nanoparticles\, nano/bioglass\, and nanocrystals) with tunable physicochemical properties for elucidating the mechanisms of different cellular communications\, human healthcare sensing\, tissue healing\, and regeneration towards advanced therapeutics.
URL:https://be.iisc.ac.in/event/be-seminar-from-design-to-healing-engineering-stimuli-responsive-function-biomaterials-for-advanced-therapeutics/
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20251008T160000
DTEND;TZID=Asia/Kolkata:20251008T170000
DTSTAMP:20260406T044302
CREATED:20250930T060853Z
LAST-MODIFIED:20250930T060853Z
UID:4395706-1759939200-1759942800@be.iisc.ac.in
SUMMARY:BE Seminar: Deleting the Genome: Quantitative Imaging Approaches to Design Nanomedicine Delivery Strategies
DESCRIPTION:Speaker: Prof. Jeremy Simpson\nCollege Principal & Dean of Science\nUCD College of Science \nDate: 8th October 2025\nTime: 4.00 PM \nVenue: Classroom- 624(6th Floor)\, TCS Smart X Hub (TSH) Building \nTitle: Deleting the Genome: Quantitative Imaging Approaches to Design Nanomedicine Delivery Strategies \nAbstract: Quantitative biological imaging approaches can be used to study a wide range of phenomena in basic cell biology as well as applications in biotechnology and bioengineering. In this seminar\, I will describe our high-content imaging technology platform and how it provides insight into trafficking pathways in cells\, a number of specific human diseases\, as well as how nanoparticles\, as therapeutic carriers\, deliver their cargo into cells. I will also present some of our current work illustrating how we use high-content imaging to study 3D cell models\, which together provide us with the opportunity to interrogate cell function at the molecular level\, in turn making valuable contributions to our wider understanding of human disease and therapeutic options. \nAbout The Speaker: Prof. Simpson is an internationally renowned cell biologist with over two decades of experience in prestigious institutions across the UK\, USA\, and Germany. As Dean of Science at UCD\, he leads over 5\,300 students and 750 staff members. He also heads the UCD Cell Screening Laboratory\, conducting pioneering research in cellular dysfunction and nanoparticle-based targeted drug delivery. With more than 130 peer-reviewed publications and numerous global lectures\, Prof. Simpson brings unmatched academic depth and insight to this engagement.
URL:https://be.iisc.ac.in/event/be-seminar-deleting-the-genome-quantitative-imaging-approaches-to-design-nanomedicine-delivery-strategies/
CATEGORIES:Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Kolkata:20260129T120000
DTEND;TZID=Asia/Kolkata:20260130T173000
DTSTAMP:20260406T044302
CREATED:20260121T110222Z
LAST-MODIFIED:20260121T111018Z
UID:4396133-1769688000-1769794200@be.iisc.ac.in
SUMMARY:BE Symposium 2026
DESCRIPTION:12th Annual Symposium\, BE 2026\nThe Department of Bioengineering at the Indian Institute of Science (IISc) is delighted to announce its 12th Annual Research Symposium\, which will be held on 29th–30th January 2026 at the G22 Seminar Room\, TCS Smart-X Hub Building\, IISc Bangalore. \nThe symposium brings together researchers\, academicians\, and industry professionals to discuss cutting-edge advancements in bioengineering. The event will feature a series of keynote lectures\, spotlight sessions\, trailblazer student talks\, and poster presentations. \nThe symposium provides a platform to showcase innovative research through trailblazer talks by young researchers and interactive poster sessions. \nWe invite researchers\, students\, and industry professionals to join us for two days of engaging discussions\, knowledge sharing\, and networking opportunities. \n  \nBE Symposium 2026 Brochure: Click here \n  \n			\n			\n				\n				\n				\n				\n			\n				\n				\n				\n				\n				\n				\n				\n				\n				\n				\n				\n			\n			\n				\n				\n				\n				\n			\n				\n				\n				\n				\n				\n				\n				\n				\n				\n				\n				Program Schedule\n \nJan 29\, 2026\n \nTime: 12:00 PM – 6:00 PMVenue: G22 seminar room\, TCS Smart-X Hub building\, IISc Bangalore \n\n\n\nTime\nEvent\n\n\n12:00 – 2.10 pm\nRegistration\n\n\n2:10 pm\nWelcome remark\nProf. Kaushik Chatterjee\, Chair\, BE\n\n\n2:15 pm\nOpening remark\nProf. Navakanta Bhat\, Dean\, Division of Interdisciplinary Sciences\n\n\n2:25 pm\nIntroduction to Memorial Talk \nDr. Ajay Tijore\, BE\n\n\n2:30 pm\nProf. Sanjay Biswas Memorial Talk \nDr. Sanghamitra Pati\, Additional Director General\, Indian Council of Medical Research (ICMR)\, Delhi\n\n\n3:30 – 4:00 pm\n     Coffee Break & Poster Session \n\n\n\n4:00 – 4:30 pm\nSpotlight talk\nDr. Juhi Singh\, IISc\n\n\n4:30 – 5:00 pm\nSpotlight talk\nDr. Meenakshi Kamaraj\, IISc\n\n\n5:00 – 6:00 pm\nPoster Session\n\n\n\n\n\n  \nJan 30\, 2026\n \nTime: 10:00 AM – 5:30 PMVenue: G22 seminar room\, TCS Smart-X Hub building\, IISc Bangalore \n\n\n\nTime\nEvent\n\n\n10:00 am\nSpotlight talk\nDr. Sanhita Sinharay\, IISc\n\n\n10:30 am\nTrailblazer Talk\nDr. Roshini P\n\n\n10:45 am\nTrailblazer Talk\nPrem Singh Anant\n\n\n11:00 am\nTrailblazer Talk\nVijaya Vaishnavi V\n\n\n11:15 – 11:45 am\nCoffee Break & Poster Session \n\n\n11:45 am\nSpotlight talk\nDr. Medhavi Vishwakarma\, IISc\n\n\n12:15 pm\nTrailblazer Talk\nIsha Akte\n\n\n12:30 pm\nTrailblazer Talk\nAkhilesh Agarwal\n\n\n12:45 pm\nTrailblazer Talk\nRashmita Luha\n\n\n1:00 – 2:00 pm\nLunch\n\n\n2:00 – 3:00 pm\nPoster Session \n\n\n3:00 pm\nIndustry Talk \nDr. Aditya Kulkarni\, Senior Scientific Manager\, Biocon Ltd. Bangalore \n\n\n3:30 pm\nTrailblazer Talk\nDr. Sulob Roy Chowdhury\n\n\n3:50 pm\nTrailblazer Talk\nDr. Akshi Vashishtha\n\n\n4:10 – 4:30 pm\nCoffee Break & Poster Session \n\n\n4:30 pm\nSpotlight talk\nProf. Mohit Kumar Jolly\, IISc\n\n\n5:00 pm\nTrailblazer Talk\nShivaani E\n\n\n5:15 pm\nTrailblazer Talk\nHarshavardhan B V\n\n\n5:30 pm\n\nClosing remarks and vote of thanks
URL:https://be.iisc.ac.in/event/be-symposium-2026/
LOCATION:IDR Building – G22 Seminar Room
CATEGORIES:Announcement,Seminar
ATTACH;FMTTYPE=image/png:https://be.iisc.ac.in/wp-content/uploads/2026/01/12th-Annual-Symposium-BE-2026.png
END:VEVENT
END:VCALENDAR