BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Department of Bioengineering - ECPv5.14.0.2//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Department of Bioengineering
X-ORIGINAL-URL:https://be.iisc.ac.in
X-WR-CALDESC:Events for Department of Bioengineering
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:UTC
BEGIN:STANDARD
TZOFFSETFROM:+0000
TZOFFSETTO:+0000
TZNAME:UTC
DTSTART:20230101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=UTC:20231009T160000
DTEND;TZID=UTC:20231009T170000
DTSTAMP:20260407T184111
CREATED:20231003T233354Z
LAST-MODIFIED:20231003T233354Z
UID:4394278-1696867200-1696870800@be.iisc.ac.in
SUMMARY:Seminar by Dr. Mahipal Ganji on "Decoding the Stabilizing Energetics of DNA and Their Applications in DNA Nanotechnology and Super-resolution Imaging"
DESCRIPTION:The Department of Bioengineering (BE) cordially invites you to attend a Departmental Seminar. \nSpeaker: Dr. Mahipal Ganji\nDepartment name: Dept. of Biochemistry\, IISc. \nTitle: Decoding the Stabilizing Energetics of DNA and Their Applications in DNA Nanotechnology and Super-resolution Imaging \nAbout the Speaker: Mahipal studied Physics at Nizam College Hyderabad\, India\, and Nanobiophysics at TU Dresden\, Germany\, followed by a PhD from Bionanoscience department at TU Delft\, the Netherlands. After short stint as postdoc at the same institute\, did a postdoctoral work at the Max-Planck Institute of Biochemistry\, Martinsried Germany. His research is interested in understanding how genome is organized in a small compartment. We develop tools to understand factors that alter genome organization using single-molecule imaging and super-resolution microscopy approaches. \nAbstract:\nIn the realm of biology\, DNA within our cells constantly undergoes deformations\, unwinding and rewinding\, yet remarkably\, genetic information is efficiently passed down through generations. In my talk\, I will delve into our recent endeavors aimed at unraveling the world of stabilizing energetics within DNA. Specifically\, we have developed an innovative multiplexed single-molecule assay\, harnessing the power of DNA-PAINT super-resolution imaging and DNA nanotechnology. This advanced imaging technology enables us to conduct unbiased kinetic analyses of multiple stacking interactions in a single experiment. Our data reveals that the stability of individual dinucleotide interactions varies dramatically\, allowing us to implicate them in diverse applications. During my presentation\, I will explore their implications in understanding the mechanical properties of single-stranded DNA. Furthermore\, I will discuss how these discoveries are paving the way for the development of efficient imaging probes and their relevance to the field of DNA nanotechnology.
URL:https://be.iisc.ac.in/event/seminar-by-dr-mahipal-ganji-on-decoding-the-stabilizing-energetics-of-dna-and-their-applications-in-dna-nanotechnology-and-super-resolution-imaging/
LOCATION:CES Seminar Hall\, CES Seminar Hall\, 3rd Floor\, Biological Science Building
CATEGORIES:Seminar
END:VEVENT
END:VCALENDAR