A distinguishing feature of BSSE is the conscious attention given to working with clinicians, clinical researchers, and hospitals. We have MoUs with a number of hospitals in and outside Bengaluru. Additionally, we have a special MD-PhD programme with CMC-Vellore. We have two DBT-supported "biodesign innovator" positions for MD-degree holders to pursue development of innovative biomedical devices. We get MBBS students from CMC-Vellore for a summer programme (see BEST+) every year. Most importantly, many of our past and ongoing projects have clinical collaborators. Some of those projects are listed below.

  1. Analysis of Hemoglobin Variants-Phase 2 with St. Johns Hospital, Bengaluru
  2. Urinary and kidney tissue proteomics in Adult Nephrotic Syndrome, St. Johns Hospital, Bengaluru
  3. A brain-function index apparatus to neurologically evaluate cognition, St. Johns Hospital, Bengaluru
  4. Cognitive and Auditory Rehabilitation for Elderly, St. Johns Hospital, Bengaluru
  5. Assistive Technology for Early Diagnosis of Neuro-motor Development Delay and Restriction in Infants with St. Johns Hospital, Bengaluru
  6. Development of a prototype device incorporating voice and breath sound analysis for quantification and monitoring of asthma, St. Johns Hospital, Bengaluru
  7. Development of a prototype device for the diagnosis of Obstructive Sleep Apnea using snore derived respiratory signal and pulse oximetry, with, St. Johns Hospital, Bengaluru
  8. Biopsy Needle Guidance Systems using Micro-acoustic Emitter, St. Johns Hospital, Bengaluru
  9. Neuro-protective Intervention in a Realistic, Neurophysiological model of Stroke in Rats, St. Johns Hospital, Bengaluru
  10. Intraoperative Ultrasound Tomographic Systems for Guidance in Spinal Surgery, Fortis Hospital Bengaluru
  11. Bladder contractility and dystrophy with, Mazumdar Shaw Medical Foundation, Bengaluru
  12. Surface-engineered Dental/Orthopedic Implants, with Mazumdar Shaw Medical Foundation, Bengaluru
  13. Mechano-diagnostics for RBC related diseases, CMC Vellore
  14. Microfluidic-based 3D cell culture system to evaluate the response of primary breast tumor cells to therapeutics, with MSCTR
  15. PVDF-BT composites with piezoelectric properties for artificial muscle and neural patch applications with MS Ramaiah Hospitals Bengaluru
  16. 3D Printing of Biomedical Devices, MS Ramaiah, Bengaluru
  17. Towards Deciphering the Interaction between Diabetes and Cancer MSMF, Narayana Hospitals, Bengaluru
  18. Cellular Engineering using Bio-microfluidics, Bhupesh Mehta, NIMHANS, Bengaluru
  19. Modeling and visualization of tissues for endoscopy simulators, with AIG-Hyderabad
  20. Narendra Dixit with Dr. Anita Shet, from St. John's Medical Hospital, Bangalore.
  21. Hanudatta Athreya with Dr. Sairam Geethanath of Dayanand Sagar Hospital, Bangalore.
  22. Saumitra Das with Dr. Shiv Sarin's group at Institute of Liver and Biliary Sciences, New Delhi; Dr. Rakesh Agarwal, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.
  23. Anu Rangarajan with a) Drs. Geeta Mukherjee (Pathologist), Rekha V Kumar (pathologist) and Vijaykumar (Surgeon) of Kidwai Memorial Institute of Oncology, and b) with Dr. Veena Prabhakar (Plastic surgeon) of MS Ramaiah Hospital, Bangalore.
  24. Bikramjit Basu with Dr. D. C.Sundaresh, MS Ramaiah Hospital, Bangalore, and Dr. Ajay Puri, Tata Memorial Center, Mumbai.
  25. Namrata Gundiah with Dr Julius Punnen, Cardiothoracic Surgery department, Narayana Health Hospitals, Bangalore ; with Dr Aarathi Rau, Histopathology department, MS Ramaiah Memorial Hospital, Bangalore.
  26. Namrata Gundiah and G. K. Ananthasuresh with Dr T. S. Sridhar, Molecular Medicine department, St. John's Research Institute, Bangalore.
  27. G. K. Ananthasuresh and Ashitava Ghosal with Asian Institute of Gastroenterology, Hyderabad.
  28. Ashitava Ghosal with Dr. Ramesh Makam of BEST Institute, Bangalore.
  29. G. K. Ananthasuresh, Navakanta Bhat, and K. N. Bhat with Dr. Umamaheswara Rao at NIMHANS, Bangalore.

List of Hospitals

  • St. Johns Hospital, Bengaluru
  • NIMHANS, Bengaluru
  • Narayana Hospitals, Bengaluru
  • CMC Vellore
  • AIG-Hyderabad
  • MS Ramaiah Hospitals Bengaluru
  • Mazumdar Shaw Medical Foundation, Bengaluru

Research and education in BSSE are enhanced significantly through industry interactions. Biomedical industry helps us devise the strategies in taking up problems of interest and also assessing the feasibility and market potential of transferable outcomes of research. They also advise us regarding the skills to be acquired by students aspiring to join the biomedical industry. In addition to interactions BSSE faculty have with industries, workshops are held occasionally to seek input from the industries. An industry consortium will be formed to engage the interested biomedical industries for continuous interactions. The members of the consortium will have privileged access to BSSE facilities, faculty, and students. Interested industries may please contact us.

The Centre for BioSystems Sciences and Engineering (BSSE) is an interdisciplinary department, which undertakes research and training in various disciplines related to human health. Students from colleges within the region have been visiting our department and we are glad to provide them some exposure about cutting-edge research in the broad field of bioengineering. The purpose of such visits is to help them interact with leading experts in the field of study, enhance their understanding, and perhaps motivate them to choose research as a career. The program for such visits usually includes short lectures followed by lab tours to various experimental facilities.

Lectures: short lectures in major research areas will be delivered to provide brief introduction about the research in the field before visit to the labs.

  1. Biomaterials: this particular topic will define the biomaterials, need of biomaterials, material properties and fabrication techniques to design biomaterials/devices.
  2. Biomechanics: this topic will explain how cell behavior changes with change in the cell structures. This will provide an idea how one can design diagnostic tools on the basis of change in the cellular mechanics.
  3. Advanced microscopy: this topic will provide overview of the importance of microscopy in the field of bioengineering. This topic will briefly provide details about various microscopy techniques in the bioengineering field and also will discuss what information one can get with different techniques.
  4. Microfluidics: Cell behavior can be altered with changing its environment. For example, change in chemical environment of cells would lead to change in cell migration or differentiation. This topic will provide several ways to alter cell’s environment using microfluidics and basis of design devices to analyze biological response.

After briefing about the research at BSSE, visitors will see the following facilities:

  1. Fabrication facilities: Various fabrication techniques are used to design material and devices for the biomedical applications. Visitors will get a chance to explore these techniques, for example, lithography, electropinning, spin coating etc.

  2. Characterization facilities: Atomic force microscopy, electron microscopy and confocal microscopy are used frequently in the field of bioengineering to characterize device or cell behavior. Visitors will get a chance to visit these facilities and also can interact with people who use these facilities frequently in their research work.

  3. Biomaterials lab: Visitors will also get the chance to see mammalian cell and bacterial cell culture labs, where the compatibility and will antimicrobial activity of different biomaterials are studied.

  4. Biomechanics lab: BSSE has developed devices to manipulate cell behavior using mechanical forces and also for diagnostic purpose. Visitors will get opportunity to understand the designing and operation of such devices.

  5. The college interested in visiting BSSE@IISc should contact Ms. H. S. Sunanda (sunanda@be.iisc.ernet.in)

To be updated