{"id":1379,"date":"2022-10-26T08:29:39","date_gmt":"2022-10-26T08:29:39","guid":{"rendered":"https:\/\/be.iisc.ac.in\/~mkjolly\/?page_id=1379"},"modified":"2026-07-02T14:10:16","modified_gmt":"2026-07-02T08:40:16","slug":"preprints","status":"publish","type":"page","link":"https:\/\/be.iisc.ac.in\/~mkjolly\/preprints\/","title":{"rendered":"Preprints"},"content":{"rendered":"\n

Preprints<\/h4>\n\n\n\n

<\/p>\n\n\n\n

Early Detection of Sudden Transitions in Notch signaling.<\/strong>
Tikader B<\/span>, Sarkar S, Sinha SK, Levine H,Jolly MK<\/strong>, Dutta PS (2026). bioRxiv:703083<\/a><\/p>\n\n\n\n

Decoupling of spatial scales in breast pathology reveals fractal-like nuclear organization emergent from tissue spatial architecture.<\/strong>
Das A<\/span>, Ahammer H, Prabhu JS, Bhat R, Jolly MK<\/strong> (2026). MedRxiv:26352267<\/a><\/p>\n\n\n\n

Interplay Between Immune Checkpoint Modulators and the Epithelial-to-Mesenchymal Transition Axis in Clear Cell Renal Cell Carcinoma.<\/strong>
Poddar A, Nield FA, Sharma R, Subhadarshini S<\/span>, Jolly MK<\/strong>, Ramakrishna S, Raza A, Shukla R, Kannourakis G, Jayachandran A, Prithviraj P (2026).Preprints:202604.213<\/a><\/p>\n\n\n\n

Bidirectional coupling among EMT, AXL-RB1 signaling and lineage switch drives resistance to osimertinib and worse clinical outcomes in NSCLC.<\/strong>
Vashista S<\/span>, Meena RK<\/span>, Kulkarni P, Salgia R, Thomas A, Jolly MK<\/strong> (2026). bioRxiv: 719547<\/a><\/p>\n\n\n\n

Time-dependent memory of hypoxia exposure influences tumor invasion dynamics.<\/strong>
Sadhu G<\/span>, Jain P<\/span>, Meena RK<\/span>, George JT, Jolly MK<\/strong> (2026). bioRxiv: 716866<\/a><\/p>\n\n\n\n

A Single Equation Explains Go-or-Grow Dynamics in Cyclic Hypoxia.<\/strong>
Sadhu G<\/span>, Maini PK, Jolly MK<\/strong>. arxiv: 23042<\/a><\/p>\n\n\n\n

Traveling Wave Analysis of a Go-or-Grow Invasion Model with ECM-Regulated Phenotypic Switching.<\/strong>
Sadhu G<\/span>, Jolly MK<\/strong>, Maini PK. bioRxiv: 720361<\/a><\/p>\n\n\n\n

Multi-team conflict resolution is ineffective for stable decision making.<\/strong>
Haldar K, Anand V<\/span>, Moger A, Gedeon T, Hari K<\/span>, Jolly MK<\/strong> (2025). bioRxiv: 679762<\/a><\/p>\n\n\n\n

A phenotype-structured PDE framework for investigating the role of hypoxic memory on tumor invasion under cyclic hypoxia<\/strong>.
Sadhu G, Jain P<\/span>, George JT, Jolly MK<\/strong> (2025). bioRxiv: 684650<\/a><\/p>\n\n\n\n

Interconnected axes of phenotypic plasticity drive coordinated cellular behaviour and worse clinical outcomes in breast cancer.<\/strong>
Meena RK<\/span>, Fan Y, Soundharya R<\/span>, Pandey AJ<\/span>, Kannan A, Subramanian Y, Subramanian Y, George JT, Jolly MK<\/strong> (2025). bioRxiv: 688595<\/a><\/p>\n\n\n\n

Regulatory network and spatial modeling reveal cooperative mechanisms of resistance and immune escape in ER+<\/sub> breast cancer.<\/strong>
Yijia Fan, Sahoo S,<\/span> Jolly MK<\/strong>, George JT (2025). bioRxiv: 679692<\/a><\/p>\n\n\n\n

Multi-omics investigation reveals molecular determinants of cancer cell evolution on soft extracellular matrix.<\/strong>
Sahoo S, Khanna S<\/span>, Wang TC, Lele TP, Jolly MK<\/strong> (2025). bioRxiv: 694784<\/a><\/p>\n\n\n\n

Distinct geometrical landscapes distinguish between modes of tristability in gene regulatory networks.<\/strong>
Duddu AS<\/span>, Jolly MK<\/strong>, Raju A (2025). bioRxiv: 681792<\/a><\/p>\n\n\n\n

Fixed points and multistability in monotone Boolean network models.<\/strong>
Adigwe S, BV Harshavardhan<\/span>, Jolly MK<\/strong>, Tom\u00e1\u0161 Gedeon (2025). bioRxiv: 682751<\/a><\/p>\n\n\n\n

ONCOchannelome: A computational framework for investigating altered ion channels across tumor types.<\/strong>
Parthasarathi KTS, Soundharya R<\/span>, Jolly MK<\/strong>, Jyoti Sharma (2025). bioRxiv: 685767<\/a><\/p>\n\n\n\n

How memory and adaptation cost shape cell phenotypic dynamics in response to fluctuating environments.<\/strong>
Jain P<\/span>, Jolly MK#<\/sup><\/strong>, George JT#<\/sup><\/strong> (2025). bioRxiv: 655868<\/a><\/p>\n\n\n\n

Balance between autophagy and apoptosis determines anoikis resistance: a mathematical model on cell fate<\/strong>.
Maiti S, Chedere A, Jolly MK<\/strong>, Chandra N, Rangarajan A (2025). bioRxiv: 658583<\/a><\/p>\n\n\n\n

Multiscale modeling predicts dependence of mesenchymally transitioned tumor niche fitness on cell-cell and cell-matrix adhesions.<\/strong>
Prasanna CVS<\/span>, Jolly MK#<\/sup><\/strong>, Bhat R#<\/sup><\/strong> (2025). bioRxiv: 661486<\/a><\/p>\n\n\n\n

Gain of Function p53 mutant R273H confers distinct methylation profiles and consequent partial or full EMT states to colon tumour.
<\/strong>Rani H, Subhadarshini S<\/span>, Jolly MK<\/strong>, Mahadevan V (2025). bioRxiv: 662954<\/a><\/p>\n\n\n\n

Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells.<\/strong>
Goutham S, Gopikrishnan A, BV Harshavardhan<\/span>, Venas N, Sabarinathan RK, Jolly MK<\/strong>, Bhat R (2024). bioRxiv: 616763<\/a><\/p>\n\n\n\n

Mechano-sensing role of oncogenic lncRNA NEAT1 on soft vs. stiff substrates and its implications for glioblastoma progression<\/strong>.
Ghosh A, Soundharya R<\/span>, Jolly MK<\/strong>, Majumder A (2024). bioRxiv: 624463<\/a><\/p>\n\n\n\n

Cell-autonomous BMP signaling plays a key role in the maintenance of tumour cell EMT and migration programs in human ovarian carcinoma.<\/strong>
Joun G, Zolghadr F, Chakraborty P, Yen LLT, Chong JJH, Bowtell D, DeFazio A, Jolly MK<\/strong>, Seyedasli N (2023). bioRxiv: 538847<\/a><\/p>\n\n\n\n

Mechanistic modeling of the SARS-CoV-2 and immune system interplay unravels design principles for diverse clinicopathological outcomes.<\/strong>
Sahoo S, Hari K<\/span>, Jhunjhunwala S#<\/sup><\/strong>, Jolly MK#<\/sup><\/strong> (2020). bioRxiv: 097238<\/a><\/p>\n\n\n\n

AMPK-Fyn signaling promotes Notch1 stability to potentiate hypoxia-induced breast cancer stemness and drug resistance.<\/strong>
Lahiry M, Kumar S, Hari K<\/span>, Chedere A, Jolly MK#<\/sup><\/strong><\/strong>, Rangarajan A#<\/sup><\/strong> (2020). bioRxiv: 458489<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Preprints Early Detection of Sudden Transitions in Notch signaling.Tikader B, Sarkar S, Sinha SK, Levine H,Jolly MK, Dutta PS (2026). bioRxiv:703083 Decoupling of spatial scales in breast pathology reveals fractal-like nuclear organization emergent from tissue spatial architecture.Das A, Ahammer H, Prabhu JS, Bhat R, Jolly MK (2026). MedRxiv:26352267 Interplay Between Immune Checkpoint Modulators and theContinue reading “Preprints”<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1379","page","type-page","status-publish","hentry","entry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages\/1379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/comments?post=1379"}],"version-history":[{"count":39,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages\/1379\/revisions"}],"predecessor-version":[{"id":2371,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages\/1379\/revisions\/2371"}],"wp:attachment":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/media?parent=1379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}