{"id":1441,"date":"2022-10-29T05:11:18","date_gmt":"2022-10-29T05:11:18","guid":{"rendered":"https:\/\/be.iisc.ac.in\/~mkjolly\/?page_id=1441"},"modified":"2022-10-29T05:41:37","modified_gmt":"2022-10-29T05:41:37","slug":"mechanisms-underlying-phenotypic-heterogeneity","status":"publish","type":"page","link":"https:\/\/be.iisc.ac.in\/~mkjolly\/mechanisms-underlying-phenotypic-heterogeneity\/","title":{"rendered":"Mechanisms underlying phenotypic heterogeneity"},"content":{"rendered":"\n<ol class=\"wide wp-block-list\"><li><span style=\"text-decoration: underline;\">Jain P<\/span>, Bhatia S, Thompson EW<strong><sup>#<\/sup><\/strong>, <strong>Jolly MK<sup>#<\/sup><\/strong> (2022). Population dynamics of epithelial-mesenchymal heterogeneity in cancer cells. <a href=\"https:\/\/doi.org\/10.3390\/biom12030348\"><em>Biomolecules<\/em>, 12 (3): 348\u00a0<\/a><\/li><\/ol>\n\n\n\n<ol start=\"2\" class=\"wide wp-block-list\"><li><span style=\"text-decoration: underline;\">Duddu AS, Majumdar SS, Sahoo S<\/span>, Jhunjhunwala S, <strong>Jolly MK<sup>#<\/sup><\/strong> (2022). Emergent dynamics of a three-node regulatory network explain phenotypic switching and heterogeneity: a case study of Th1\/Th2\/Th17 differentiation. <a href=\"https:\/\/doi.org\/10.1091\/mbc.e21-10-0521\"><em>Molecular Biology of the Cell<\/em>, 33 (6): ar46\u00a0\u00a0<\/a><\/li><\/ol>\n\n\n\n<ol start=\"3\" class=\"wide wp-block-list\"><li><span style=\"text-decoration: underline;\">Pillai M,<\/span> <strong>Jolly MK<sup>#<\/sup><\/strong> (2021). Systems-level network modeling deciphers the master regulators of phenotypic plasticity and heterogeneity in melanoma. <a href=\"https:\/\/doi.org\/10.1016\/j.isci.2021.103111\"><em>iScience, <\/em>24: 103111\u00a0<\/a><\/li><\/ol>\n\n\n\n<ol start=\"4\" class=\"wide wp-block-list\"><li>Brown MS, Abdollahi B, Wilkins OM, Lu H,\u00a0<span style=\"text-decoration: underline;\"> Chakraborty P<\/span>, Ognjenovic NB, Muller KE, <strong>Jolly MK<\/strong>, Christensen BC, Hassanpour S, Pattabiraman D (2022). Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer. <a href=\"https:\/\/doi.org\/10.1126\/sciadv.abj8002\"><em>Science Advances, <\/em>8 (31): abj8002<\/a>\u00a0<\/li><\/ol>\n\n\n\n<ol start=\"5\" class=\"wide wp-block-list\"><li><span style=\"text-decoration: underline;\">Singh D<\/span>, Bocci F, Kulkarni P, <strong>Jolly MK<sup>#<\/sup><\/strong> (2021). Coupled feedback loops involving PAGE4, EMT and Notch signaling can give rise to non-genetic heterogeneity in prostate cancer cells. <a href=\"https:\/\/doi.org\/10.3390\/e23030288\"><em>Entropy<\/em>, 23 (3): 288<\/a>\u00a0<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Jain P, Bhatia S, Thompson EW#, Jolly MK# (2022). Population dynamics of epithelial-mesenchymal heterogeneity in cancer cells. Biomolecules, 12 (3): 348\u00a0 Duddu AS, Majumdar SS, Sahoo S, Jhunjhunwala S, Jolly MK# (2022). Emergent dynamics of a three-node regulatory network explain phenotypic switching and heterogeneity: a case study of Th1\/Th2\/Th17 differentiation. Molecular Biology of the Cell,<a class=\"more-link\" href=\"https:\/\/be.iisc.ac.in\/~mkjolly\/mechanisms-underlying-phenotypic-heterogeneity\/\">Continue reading <span class=\"screen-reader-text\">&#8220;Mechanisms underlying phenotypic heterogeneity&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1441","page","type-page","status-publish","hentry","entry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages\/1441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/comments?post=1441"}],"version-history":[{"count":2,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages\/1441\/revisions"}],"predecessor-version":[{"id":1461,"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/pages\/1441\/revisions\/1461"}],"wp:attachment":[{"href":"https:\/\/be.iisc.ac.in\/~mkjolly\/wp-json\/wp\/v2\/media?parent=1441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}