BE210 Drug Delivery: Principles and Applications
This 3-credit course is taught in August semester. This course aims to introduce concepts of drug delivery for medical challenges. The course is designed to be modular, with each module focusing on the following topics: Diffusion and permeation of drugs in biological systems; Pharmacokinetics and pharmacodynamics; Challenges and strategies for various drug delivery routes; Drug delivery systems: polymer‐drug conjugates, matrix based systems, reservoir and erodible systems; Responsive and targeted delivery systems; Nanotoxicology and Regulatory pathways. Course is open to all students registered for a PhD programme at IISc and to undergraduates who have completed their 2nd year.
Note: This course is also offered through the online NPTEL platform for everyone in the world. To check it out click here and here
BE206 Biology for Engineers
The course provides an introduction to fundamental concepts in Biology for PhD students with little to no knowledge of Biology past 10th or 12th standard school curriculum. The course will cover the following topics: biomolecules, fundamentals of biochemistry, protein structure and function, basic molecular biology, genetics, and an introduction to the cellular architecture. A combination of theoretical concepts and basic experimental methodologies in biology will be discussed. In addition, an introduction to how cells form tissues will be covered, which includes lectures on classification of tissues. The concepts covered here will aid in the skill development required to study diverse problems in bioengineering.
BE214 Fundamentals of Bioengineering
This course covers essentials of biomaterials and cell and tissue mechanics. It caters to those who want to get first exposure to the topics, which lays the foundation for advanced courses in these two topics.
Part I of the course will cover biomaterials: polymers (synthesis and properties), metals, ceramics, biocompatibility, biodegradability, key properties of biomaterials (mechanical, chemical and physical properties), protein adsorption, host response to biomaterials (innate immune response, blood coagulation and complement response), fibrosis, implant associated infections, drug delivery, tissue engineering
Part II of the course will cover cell and tissue mechanics: Cell and tissue types, Viscoelasticity of cells and tissues, mechanics of cells: cytoskeleton: contractility and movement, molecular motors for transportation within the cells, Signal transduction within the cells to achieve basic mechanics, cellular forces, stiffness sensing of cells, wound healing, mechanics of multi-joint posture and movement control