Preprints

Preprints

Impacts of competition and phenotypic plasticity on the viability of adaptive therapy.
Vibishan B, Jain P, Sharma V, Hari K, Kadelka C, George JT#Jolly MK# (2025). bioRxiv: 644475

Fractal measures as predictors of histopathological complexity in breast carcinoma mammograms.
Das A#, Bhat R#Jolly MK# (2025). bioRxiv: 648305

CD4+ T-cell sensitize quasi-mesenchymal breast tumors lacking CD73 to anti-CTLA4 immune checkpoint blockade therapy.
Chandrganti SR, Sams C, Sahoo S, Feng B, O’Connell I, Li L, Nepal S, Pulukuri S, Bakhle K, Thiru P, Simian C, Bell GW, Jolly MK, Dongre A (2025). bioRxiv: 653467

Bioenergetic reprogramming of macrophages reduces drug tolerance in Mycobacterium tuberculosis.
Yadav V, Sahoo S, Malhotra N, Mishra R, Rajmani RS, Shanmugam S, Shandil RK, Narayanan S, Thacker VV, Jolly MK, Seshasayee ASN, Singh A (2025). bioRxiv: 634842

An integrative molecular systems approach unravels mechanisms underlying biphasic nitrate uptake by plant nitrate transporter NRT1.1.
Subhadarshini S, Sahoo S, Jolly MK, Rashid M (2025). bioRxiv: 635294

Topological conditions of gene regulatory networks enabling robust binary cell-fate decision-making.
Shyam S, Nandhan N, Jolly MK, Hari K (2025). bioRxiv: 636066

Epithelial to Mesenchymal Transition in the Endometrium Mediated by HOXA10 drives Embryo Implantation.
Ashary N, Suresh S, Bhide A, Shyamal S, N Pranya, Mishra A, A Anuradha, Hansda S, BV Harshavardhan, Jolly MK, Modi D (2025). bioRxiv: 631632

Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells.
Goutham S, Gopikrishnan A, BV Harshavardhan, Venas N, Sabarinathan RK, Jolly MK, Bhat R (2024). bioRxiv: 616763

DNA walk of specific fused oncogenes exhibit distinct fractal geometric characteristics in nucleotide patterns.
Das A, Sehgal M, Singh A, Goyal R, Prabhakar M, Fricke J, Mambetsariev I, Kulkarni P, Jolly MK, Salgia R (2024). bioRxiv: 602166

Differential expression of oncogenic lncRNAs NEAT1 and MALAT1 in 2D monolayer vs. 3D tumoroid culture and its implications in cancer progression.
Ghosh A, Soundharya RJolly MK, Majumder A (2024). bioRxiv: 619405

A multi-level formalism to capture the characteristics of hybrid phenotypes in Epithelial-Mesenchymal Plasticity.
Hari K, Tripathi S, Anand V, Jolly MK, Levine H (2024). bioRxiv: 625479

Mechano-sensing role of oncogenic lncRNA NEAT1 on soft vs. stiff substrates and its implications for glioblastoma progression.
Ghosh A, Soundharya R, Jolly MK, Majumder A (2024). bioRxiv: 624463

Metastatic organotropism in small cell lung cancer.
Krishnamurthy M, Dhall A, Sahoo S, Schultz CW, Baird MA, Desai P, Odell J, Takahashi N, Nirula M, Zhuang S, Huang Y, Schroeder B, Zhang Y, Thomas MS, Redon C, Robinson C, Thang L, Ileva L, Patel NL, Kalen JD, Varlet AA, Sopilniak NZ, Jha A, Wangsa D, Butcher D, Morgan T, Afzal AN, Chari R, Baktiar K, Kumar S, Pongor L, Difilippantonio S, Aladjem MI, Pommier Y, Jolly MK, Lammerding J, Sharma AK, Thomas A (2024). bioRxiv: 617066

GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.
Chaudhury N, Choudhary BS, Patra S, Malvankar S, Shivashankar A, Jog E, Kailje VV, Khanna S, Manna S, Sahoo S, Soundharya R, Jolly MK, Dalal SN, Verma N (2023). bioRxiv: 541287

Cell-autonomous BMP signaling plays a key role in the maintenance of tumour cell EMT and migration programs in human ovarian carcinoma.
Joun G, Zolghadr F, Chakraborty P, Yen LLT, Chong JJH, Bowtell D, DeFazio A, Jolly MK, Seyedasli N (2023). bioRxiv: 538847

Mechanistic modeling of the SARS-CoV-2 and immune system interplay unravels design principles for diverse clinicopathological outcomes.
Sahoo S, Hari K, Jhunjhunwala S#, Jolly MK# (2020). bioRxiv: 097238

AMPK-Fyn signaling promotes Notch1 stability to potentiate hypoxia-induced breast cancer stemness and drug resistance.
Lahiry M, Kumar S, Hari K, Chedere A, Jolly MK#, Rangarajan A# (2020). bioRxiv: 458489

Feedback loops involving AMPK, ERK and TFEB in matrix detached leads to non-genetic heterogeneity.
Kumar S, Hari K, Jolly MK#, Rangarajan A# (2019). bioRxiv: 736546