Preprints
Multi-team conflict resolution is ineffective for stable decision making.
Haldar K, Anand V, Moger A, Gedeon T, Hari K, Jolly MK (2025). bioRxiv: 679762
A phenotype-structured PDE framework for investigating the role of hypoxic memory on tumor invasion under cyclic hypoxia.
Sadhu G, Jain P, George JT, Jolly MK (2025). bioRxiv: 684650
Interconnected axes of phenotypic plasticity drive coordinated cellular behaviour and worse clinical outcomes in breast cancer.
Meena RK, Fan Y, Soundharya R, Pandey AJ, Kannan A, Subramanian Y, Subramanian Y, George JT, Jolly MK (2025). bioRxiv: 688595
Regulatory network and spatial modeling reveal cooperative mechanisms of resistance and immune escape in ER+ breast cancer.
Yijia Fan, Sahoo S, Jolly MK, George JT (2025). bioRxiv: 679692
Multi-omics investigation reveals molecular determinants of cancer cell evolution on soft extracellular matrix.
Sahoo S, Khanna S, Wang TC, Lele TP, Jolly MK (2025). bioRxiv: 694784
Distinct geometrical landscapes distinguish between modes of tristability in gene regulatory networks.
Duddu AS, Jolly MK, Raju A (2025). bioRxiv: 681792
Fixed points and multistability in monotone Boolean network models.
Adigwe S, BV Harshavardhan, Jolly MK, Tomáš Gedeon (2025). bioRxiv: 682751
Androgen receptor activation stabilizes a hybrid epithelial/mesenchymal phenotype in presence of Notch-Jagged signaling.
Guha S, Soundharya R, Tikader B, Jolly MK#(2025). bioRxiv: 687414
ONCOchannelome: A computational framework for investigating altered ion channels across tumor types.
Parthasarathi KTS, Soundharya R, Jolly MK, Jyoti Sharma (2025). bioRxiv: 685767
How memory and adaptation cost shape cell phenotypic dynamics in response to fluctuating environments.
Jain P, Jolly MK#, George JT# (2025). bioRxiv: 655868
Balance between autophagy and apoptosis determines anoikis resistance: a mathematical model on cell fate.
Maiti S, Chedere A, Jolly MK, Chandra N, Rangarajan A (2025). bioRxiv: 658583
Multiscale modeling predicts dependence of mesenchymally transitioned tumor niche fitness on cell-cell and cell-matrix adhesions.
Prasanna CVS, Jolly MK#, Bhat R# (2025). bioRxiv: 661486
Gain of Function p53 mutant R273H confers distinct methylation profiles and consequent partial or full EMT states to colon tumour.
Rani H, Subhadarshini S, Jolly MK, Mahadevan V (2025). bioRxiv: 662954
CD4+ T-cell sensitize quasi-mesenchymal breast tumors lacking CD73 to anti-CTLA4 immune checkpoint blockade therapy.
Chandrganti SR, Sams C, Sahoo S, Feng B, O’Connell I, Li L, Nepal S, Pulukuri S, Bakhle K, Thiru P, Simian C, Bell GW, Jolly MK, Dongre A (2025). bioRxiv: 653467
Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells.
Goutham S, Gopikrishnan A, BV Harshavardhan, Venas N, Sabarinathan RK, Jolly MK, Bhat R (2024). bioRxiv: 616763
Differential expression of oncogenic lncRNAs NEAT1 and MALAT1 in 2D monolayer vs. 3D tumoroid culture and its implications in cancer progression.
Ghosh A, Soundharya R, Jolly MK, Majumder A (2024). bioRxiv: 619405
A multi-level formalism to capture the characteristics of hybrid phenotypes in Epithelial-Mesenchymal Plasticity.
Hari K, Tripathi S, Anand V, Jolly MK, Levine H (2024). bioRxiv: 625479
Mechano-sensing role of oncogenic lncRNA NEAT1 on soft vs. stiff substrates and its implications for glioblastoma progression.
Ghosh A, Soundharya R, Jolly MK, Majumder A (2024). bioRxiv: 624463
Metastatic organotropism in small cell lung cancer.
Krishnamurthy M, Dhall A, Sahoo S, Schultz CW, Baird MA, Desai P, Odell J, Takahashi N, Nirula M, Zhuang S, Huang Y, Schroeder B, Zhang Y, Thomas MS, Redon C, Robinson C, Thang L, Ileva L, Patel NL, Kalen JD, Varlet AA, Sopilniak NZ, Jha A, Wangsa D, Butcher D, Morgan T, Afzal AN, Chari R, Baktiar K, Kumar S, Pongor L, Difilippantonio S, Aladjem MI, Pommier Y, Jolly MK, Lammerding J, Sharma AK, Thomas A (2024). bioRxiv: 617066
GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.
Chaudhury N, Choudhary BS, Patra S, Malvankar S, Shivashankar A, Jog E, Kailje VV, Khanna S, Manna S, Sahoo S, Soundharya R, Jolly MK, Dalal SN, Verma N (2023). bioRxiv: 541287
Cell-autonomous BMP signaling plays a key role in the maintenance of tumour cell EMT and migration programs in human ovarian carcinoma.
Joun G, Zolghadr F, Chakraborty P, Yen LLT, Chong JJH, Bowtell D, DeFazio A, Jolly MK, Seyedasli N (2023). bioRxiv: 538847
Mechanistic modeling of the SARS-CoV-2 and immune system interplay unravels design principles for diverse clinicopathological outcomes.
Sahoo S, Hari K, Jhunjhunwala S#, Jolly MK# (2020). bioRxiv: 097238
AMPK-Fyn signaling promotes Notch1 stability to potentiate hypoxia-induced breast cancer stemness and drug resistance.
Lahiry M, Kumar S, Hari K, Chedere A, Jolly MK#, Rangarajan A# (2020). bioRxiv: 458489
Feedback loops involving AMPK, ERK and TFEB in matrix detached leads to non-genetic heterogeneity.
Kumar S, Hari K, Jolly MK#, Rangarajan A# (2019). bioRxiv: 736546