Deepak Kumar Saini


Dept. of Developmental Biology & Genetics

Phone : +91-80-2293-2574 (O)

Research Interests:
Signaling in aging, inflammation and infection, Two-component signaling systems in Mycobacterium tuberculosis.

Educational History

Post-doctoral fellow: Washington University Medical School (2005-2010)
Post-doctoral fellow: University of Arkansas for Medical Sciences (2004-2005)
PhD (2003): AIIMS, New Delhi, India (Biotechnology)
Masters (1997): Madurai Kamaraj University, TN, India (Biotechnology)
Bachelors (1994): Delhi University, Delhi, India (Biology)

Courses offered

RD205: Principles of Signal Transduction

Awards / Honours / Affiliations

Will be updated soon


  • Yadav, P., Shah, R., Roy, A., Jani, S., Chatterjee, K.* and Saini, D.K.* Cellular Senescence Program is Sensitive to Physical Differences in Polymeric Tissue Scaffolds. (2023) ACS Material Au. 4(1); 35-44. eCollection 2024 Jan 10.
  • Sankhe, G.D., Raja, R., Singh, D.P., Bheemireddy, S., Rana, S., Athira, P., Dixit, N.M.* and Saini, D.K*. Sequestration of histidine kinases by non-cognate response regulators establishes a threshold level of stimulation for bacterial two-component signaling. (2023) Nature Communications. 14(1):4483
  • Singh, S., Kumbhar, D., Reghu, D., Venugopal, S.J., Rekha, P.T., Mohandas, S., Rao, S., Rangaiah, A., Chunchanur, S.K.*, Saini, D.K.* and, Umapathy, S*.  Culture-Independent Raman Spectroscopic Identification of Bacterial Pathogens from Clinical Samples Using Deep Transfer Learning. (2022) Analytical Chem. 94(42): 14745-14754.
  • Ramachandran, R.V., Barman, A., Modak, P., Bhat, R., Ghosh, A.* and Saini, D.K.* How safe are magnetic nanomotors: From cells to animals. (2022) Biomaterials Advances. 140, 213048. doi: 10.1016/j.bioadv.2022.213048.
  • Fernandes, S.E., Singh, A., Rajmani, R.S., Jhunjhunwala, S. and Saini, D.K. Aging associated altered response to intracellular bacterial infections and its implication on the host. (2021) BBA Mol Cell Res. 1868(9):119063. doi: 10.1016/j.bbamcr.2021.119063
  • Yadav, P., Chatterjee, K. and Saini, D.K.Senescent Cells in 3D Culture Show Suppressed Senescence Signatures (2021)  Sci. 9(19):6461-6473. doi: 10.1039/d1bm00536g
  • Hariharan, V.N., Yadav, R.,Thakur, C., Singh, A., Gopinathan, R.,Singh, D.P., Sankhe, G., Malhotra, V., Chandra, N., Bhatt, A., Saini, D.K.(2021) Cyclic di‐GMP sensing histidine kinase PdtaS controls mycobacterial adaptation to carbon sources. The FASEB Journal. 35(4):e21475. doi: 10.1096/fj.202002537RR