Title: Elucidating and leveraging the design principles towards realistic Boolean models of gene regulatory networks Speaker: Areejit Samal (The Institute of Mathematical Sciences (IMSc), Chennai) Venue: MRDG Conference Room Abstract: Boolean networks is a widely-used mathematical framework to model gene regulatory networks. Such Boolean models consist of a set of nodes, directed edges between the nodes, and Boolean […]

Title: Tractor beams and single molecules: How to visualize and manipulate single biomolecules in real-time Abstract: Imagine you could directly see the location and dynamics of individual proteins binding to a piece of single DNA. What if you could assemble your biological complex step by step and see it in action in real-time? What if you […]

Speaker: Prof. Herbert Levine (Satish Dhawan Visiting Chair Professor, IISc) Title: Cell – ECM interactions and their relevance for cancer progression Abstract: During metastasis, tumor cells must traverse fibrous extracellular matrix (ECM) en route to the circulation. Conversely, immune cells must traverse the same medium en route to attacking a tumor. Thus, the study of the reciprocal feedbacks between […]

Speaker: Mr. Sarath Kolli, CEO of Boltzmann Labs Title: Automation of therapeutics design in the era of Artificial Intelligence Abstract:  Automation of the therapeutic design process through the integration of AI has drastically improved the efficiency and effectiveness of pharmaceutical research. With the power to assess large amounts of data within a short timeframe, AI algorithms […]

Title of Talk: Image-based biomechanics in the era of personalized medicine Speaker Name: Mirunalini Thirugnanasambandam Speaker Affiliation: Eindhoven University of Technology, Netherlands Abstract of Talk In the age of digital twins, when clinical management is moving towards a more personalized approach, it is often desired to evaluate patient-specific geometry and mechanical behavior. While ex-vivo tests […]

Speaker: Dr. Lorena Escudero Sanchez, University of Cambridge Title: AI applications in radiological image analysis for cancer research Abstract: Imaging is one of the main pillars of clinical protocols for cancer care that provides essential non-invasive biomarkers for detection, diagnosis and response assessment. The development of Artificial Intelligence (AI) tools have proven potential to transform the analysis […]

Speaker: Dr. Rati Sharma Title: Systems Biology In Action: A dive into signaling pathways and behavioral dynamics Abstract: “Systems Biology” refers to the study of biological systems through modeling, experiments and computational tools. In particular, the workings and implications of genetic networks, behavior and signal-response can be studied through the tools and techniques adapted from the field […]

Title: Molecular Imaging using CEST MRI: Acquisition, Analysis and Applications Abstract:  MRI is routinely being used to obtain different types of images that are sensitive to structural, functional, and physiological information. The use of MRI in disease diagnosis, treatment planning, and treatment monitoring is rapidly growing. Chemical-exchange-saturation-transfer (CEST) is an advanced MRI techniques which provides […]

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Title: Connecting the dynamics of microbial systems across scales Abstract:  Biological reactions often involve low-copy molecular reactants, leading to stochastic outcomes. As a result, there is substantial heterogeneity among cells, even when they experience the same external conditions. Recent theoretical and experimental investigations have demonstrated that for microbial systems such heterogeneity is of important consequence to […]

Speaker: Prof. Marty Pagel (The University of Texas MD Anderson Cancer Center, Houston, Teax ) Title: Molecular Imaging of the Tumor Microenvironment Abstract: Tumor acidosis, hypoxia and vascular perfusion are well-known characteristics of the tumor microenvironment. We have developed MRI, PET/MRI, multispectral optoacoustic tomography (MSOT) and electron paramagnetic resonance imaging (EPRI) to measure extracellular pH, […]