Siddharth Jhunjhunwala

Associate Professor

Phone : +91-80-2293-2452 (O)
E-mail: siddharth@iisc.ac.in
Website: https://jhunjhunwalalab.in/

Research Interests:
Immuno-engineering, Biomaterials, Drug Delivery

Educational History

Post-doctoral fellow: Mazumdar-Shaw International Oncology Fellow, Massachusetts Institute of Technology (2013-2015)
Post-doctoral fellow: Massachusetts Institute of Technology (2012-2013)
PhD (2011): University of Pittsburgh, Pittsburgh, USA (Bioengineering)
Bachelors (2006): Anna University, Chennai, India (Industrial Biotechnology)

Courses offered

BE229: Statistics for Bioengineers

BE301: AI for Biomedical Research (supporting Prof. Arvind Rao, Visiting Faculty)

Awards / Honours / Affiliations

  1. DBT-Wellcome India Alliance Intermediate Fellowship                      Jan. 2020 – Dec. 2024
  2. Prof. Priti Shankar Teaching Award for Assistant Professors           Mar. 2019
  3. R.I. Mazumdar Young Investigator Position at IISc                             Feb. 2017 – Jan. 2019
  4. Ramanujan Fellowship (SERB, DST, Govt. of India)                             Sept. 2016 – Dec. 2019

Publications

  • A biomaterial implant model demonstrates that immature neutrophils drive immunopathology following acute injury. Vinod Kumar Dorai, Alakesh Alakesh, Ranjitha Guttapadu, Shruthi Ksheera Sagar, Meghna Ravishankar Valakatte, Jayashree Vijaya Raghavan, Monisha Mohandas, Kalpana S R, Nagasuma Chandra, Siddharth Jhunjhunwala*. Biomaterials. 2026. 328: 123907. DOI: 10.1016/j.biomaterials.2025.123907
  • Phagosome Maturation in Macrophages is Enhanced by p38𝜶 MAPK Signaling. Mitali Shah, Nikhita Kirthivasan, Sandip Chakraborty, Yamuna Krishnan, Siddharth Jhunjhunwala*. Small. 2025. e06883. DOI: 10.1002/smll.202506883
  • Neutrophil-Derived Extracellular Vesicles for Facile Delivery of Diagnostic Agents to Tumor Microenvironments. Bartika Ghoshal, Pooja Patkulkar, Preeti Bhatt, Subinoy Rana, Sanhita Sinharay, Siddharth Jhunjhunwala*. ACS Applied Biomaterials. 2025. 8(5): 4132-4139. DOI: 10.1021/acsabm.5c00266
  • Cholesterol Levels and Monocyte Phenotype are Predictors of Non-healing in Individuals with Low Grade Diabetic Foot Ulcers: A Prospective Cohort Study. Jayashree V. Raghavan, Shruthi K. Sagar, Vinod K. Dorai, Rebecca D. Samuel, Priyanka Arunachalam, Chaluvanarayana H. C., Pavan Belahalli, Kalpana S. R., Siddharth Jhunjhunwala*. Advances in Wound Care. 2023. 6:316-322. DOI: 10.1089/wound.2021.0182
  • Immunomodulatory Bandage for Accelerated Healing of Diabetic Wounds. Jayashree V. Raghavan, Vinod K. Dorai, Shruthi K. Sagar, Archana Sivaraman, Kalpana S. R., Siddharth Jhunjhunwala*. ACS Bio & Med Chem Au. 2022. 2: 409-418. DOI: 10.1021/acsbiomedchemau.1c00063
  • Sterile Inflammation Alters Neutrophil Kinetics in Mice. Alakesh Alakesh, Thiruvickraman Jothiprakasam, Jayashree V Raghavan, Siddharth Jhunjhunwala*. Journal of Leukocyte Biology. 2022. Accepted. DOI: 10.1002/JLB.1A0321-132RR
  • The consequences of particle uptake on immune cells. Preeti Sharma, Alakesh Alakesh, Siddharth Jhunjhunwala*. Trends in Pharmacological Sciences. 2022. 43: 305-320. DOI: 10.1016/j.tips.2022.01.009
  • Particle Uptake Driven Phagocytosis in Macrophages and Neutrophils Enhances Bacterial Clearance. Preeti Sharma, Anjali Vijaykumar, Jayashree V Raghavan, Supriya R Rananaware, Alakesh Alakesh, Janhavi Bodele, Junaid Rehman, Shivani Shukla, Virta Wagde, Savitha Nadig, Sveta Chakraborti, Sandhya S Visweswariah, Dipankar Nandi, Balasubranian Gopal, Siddharth Jhunjhunwala*. Journal of Controlled Release. 2022. 343: 131-141. DOI: 10.1016/j.jconrel.2022.01.030