Speaker: Dr. Rashmi Mohanty Title: Extracellular Matrix- A Transport Barrier for Drug Delivery Abstract: Extracellular Matrix (ECM) determines crucial cellular responses through cell-matrix interactions. Specific qualitative and quantitative changes occur in the ECM during disease and, in part, regulate critical events that determine pathological tissue phenotype. For example, in solid cancers, the extraordinarily dense fibrotic […]

Speaker: Dr Siv Sivaloganathan Title: A Mathematical Odyssey: From Brain Biomechanics to Cancer Therapeutics Abstract: In this talk, I will touch on some of the successes and obstacles encountered in the application of mathematics to the biomedical sciences. I hope to illustrate this with examples from hydrocephalus, tumorigenesis, and the utilization of High-Intensity Focused Ultrasound […]

Speaker: Kundan Sengupta Title: Mechanonucleargenomics Abstract: It is well established that chromosomes occupy a unique sub-volume in the interphase nucleus referred to as Chromosome Territories. Remarkably, chromosome territories are organized in a non-random manner with gene rich chromosome territories toward the center and gene poor chromosome territories proximal to the nuclear border. What are the […]

Speaker:  Dr. Vanita Rahman Title: The Role of Nutrition in the Prevention and Reversal of Type 2 Diabetes Abstract: Non-communicable diseases, such as diabetes, obesity, and cardiovascular disease, are rising at an alarming rate in India due to the unique genetic risks of the Indian population and the westernization of the Indian diet and lifestyle. […]

Speaker: Prof. Arvind Rao Title: Machine Learning Approaches To The Interpretation Of the Tumor Microenvironment Using Spatial Immuno-profiling & Spatial Transcriptomics Abstract: Spatial profiling technologies like hyper-plex immunostaining in tissue, spatial transcriptomics, etc. have the potential to enable a multi-factorial, multi-modal characterization of the tissue microenvironment. Scalable, quantitative methods to analyze and interpret spatial patterns […]

Speaker: Prof. Sarthak Misra Prof. Satish Dhawan Visiting Chair Professor Date: 25th April 2024 Time: 2.30 pm - 3.30 pm Venue: DBG Seminar Hall Title: Surgical Robotics: A Journey Across Scales Summary: This talk will provide an overview of ongoing work at the Surgical Robotics Laboratory. It covers topics ranging from the design of macro-scale […]

Speaker: Maria Yakunina Leader of research group, Laboratory of molecular microbiology, Institute of Nanobiotechnologies, Peter the Great St.Petersburg Polytechnic University Title: The story of giant bacteriophage phiKZ and its potential usage as antimicrobials source Abstract: Bacteriophages are viruses that infect bacteria, serving as their natural enemies and our potential allies. Due to the constant arms […]

Speaker: Dr. Aarat P. Kalra IIT Delhi Title: All Wired Up: Harnessing Protein Polymers for Medicine and Nanotechnology Abstract: The successful interfacing of biochemistry with electronics is one of the grand challenges of nanotechnology. Biodegradable and biocompatible materials with structural integrity, that can perform mixed electronic and ionic roles are required for the development of […]

Title: Harnessing immune system for the development of bio-therapeutics Abstract: Leveraging the immune system for therapeutic advancement offers numerous advantages over standard treatments for inflammatory diseases. These advantages encompass precise targeting, enduring responses, minimal toxicity, and more. Diverse immunotherapies, such as antibody utilization, T-cell therapy, dendritic cell vaccination, among others, are actively under investigation. Given […]

Speaker: Dr. Rakesh Das Max-Planck-Institute for the Physics of Complex Systems, Germany Title: Physics of Nuclear Organization Abstract: Spatiotemporal organization of the subnuclear medium plays a crucial role in genome regulation . However, the effect of active perturbation from various molecular actions in the medium on this organization remains unclear. In this seminar, I will mainly […]

Title: Engineering bottom-up synthetic cells to mimic life-like functions Abstract: How did life evolve from non-living matter on early Earth, and is it possible to recreate this transition artificially in a laboratory setting? Reconstructing well-defined functional molecular entities, components, and modules from the bottom-up to create a synthetic cell will provide new insights into the […]

Title: NEXT-GENERATION SOLUTIONS IN MEDICINE: OVERCOMING DRUG RESISTANCE IN CANCER. Abstract: Research in my laboratories is focused on uncovering the underlying root causes of cancer's resistance to drugs. Specifically, the work aims to identify and validate the mechanisms that drive this resistance. After elucidating the mechanism, we have designed new nano-delivery devices specific to the target […]